ARI takes the administrative lead in responding to any allegation of research misconduct involving an HMS or HSDM faculty member or trainee. In this role, ARI staffs and provides support to the Standing Committee on Faculty Conduct. In accordance with the HMS Principles and Procedures for Dealing with Allegations of Faculty Misconduct, ARI also convenes and provides support to faculty panels appointed to review allegations of research misconduct.

ARI also disseminates guidelines for research integrity.