Harvard Medical School (HMS) supports a culture that advances research rigor, reproducibility and responsibility (R3). HMS is committed to identifying, exploring, and fostering R3 principles and practices relevant to our research community through cross-discipline conversations and collaborations. To ensure the continued advancement of research excellence at HMS, the HMS R3 effort identifies opportunities to enhance R3, with a focus on evidence-based research, institutional support, training and educational programs, and resources and tools for our students, trainees, faculty, and staff.